The first Railway Cup semi-finalists will be known by tea-time.
Champions St. George's are all but there and will confirm a last four place if they draw or beat St. John's at Glencrutchery Road.
Laxey will also qualify with a point or better from their home encounter with Castletown.
The other contenders for a slot are St. Mary's who travel to Ramsey and Peel who go to Corinthians.
At the bottom, Gymns have the chance to pull four points clear of the relegation zone if they return from bottom side Marown with three points.
In Rugby's South Lancashire and Cheshire Division Two, Douglas are looking for their nineth straight win of the season.
They welcome mid-table Southport to Port-e-Chee.
Vagabonds lost a tight game with Douglas last Saturday and will hope to get back to winning ways at Moore.
And Ramsey have a big relegation encounter away to Marple but confidence will be high after good performances in their last two fixtures.
Following their narrow victory over Champions Valkyrs "A" last week, Bacchas "A" can go two points clear at the top of the Mixed Hockey Premier League.
They play Vikings "A" who lost any realistic chance of staying in the title race when they lost 3-2 to Bacchas "B" on Thursday evening.
The other top flight encounter is between Valkyrs "B" and Vikings "B".
The rest of the day's programme is made up of first round Mixed Hockey Plate ties.